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Image Search Results
Journal: PLOS ONE
Article Title: Helicase-like transcription factor (HLTF) -deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in lymphatic intravascular metastatic niches
doi: 10.1371/journal.pone.0291023
Figure Lengend Snippet: Source, application and concentration of antibodies.
Article Snippet:
Techniques: Concentration Assay, Recombinant, Plasmid Preparation
Journal: PLOS ONE
Article Title: Helicase-like transcription factor (HLTF) -deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in lymphatic intravascular metastatic niches
doi: 10.1371/journal.pone.0291023
Figure Lengend Snippet: Summary of site-specific S-glutathionylation identified by 2D-DIGE MALDI-TOF/TOF mass spectrometry. Pr-SSG in HLTF -/- CDX/TME.
Article Snippet:
Techniques: Mass Spectrometry
Journal: PLOS ONE
Article Title: Helicase-like transcription factor (HLTF) -deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in lymphatic intravascular metastatic niches
doi: 10.1371/journal.pone.0291023
Figure Lengend Snippet: Light micrographs show positive immunostaining for PDPN (A), a lymphatic-specific endothelial cell marker, in companion with PGAM1 (B), ENOA1 (C) and ANXA1 (D) in tumor cells. 40X magnification. ANXA1 (E) and PGAM1 (F) colocalize (G) in tumor and endothelial cells in lymphatic intravascular niches. A polarized extravascular tumor cell with redistribution of ANXA1 and PGAM1 into a posterior uropod protrusion (yellow insets) is engaged in amoeboid migration, a hallmark of rapid migration . The maximal projection of confocal images obtained from a z stack (500 nm slice) using a 60x objective (oil) are shown. Overlay images were obtained with transmitted light and excitation at 405 nm (DAPI, blue-violet), 555 nm (ANXA1, green) and 647 nm (PGAM1, red).
Article Snippet:
Techniques: Immunostaining, Marker, Migration